Mudcat Café message #1485963 The Mudcat Café TM
Thread #81236   Message #1485963
Posted By: freda underhill
16-May-05 - 08:29 AM
Thread Name: BS: Nicotine vaccination may cure addiction
Subject: BS: Nicotine vaccination may cure addiction
New hope to beat tobacco addiction; Kate Jones, medical reporter
16 may 05;

CLINICAL trials on a new vaccine against smoking have raised hopes it could prevent cigarette addiction. After being injected with the vaccine, some smokers were able to kick the habit immediately, results of the first large human trial reveal. Tests on more than 340 smokers showed 57 per cent of those injected with the highest dose of the vaccine quit. And 32 per cent of smokers who received low-dose vaccine levels were able to butt out. Of those injected with a placebo, 31 per cent stopped smoking.

The drug works by combining nicotine with antibodies in the bloodstream, blocking nicotine from entering the brain and shutting down the body's addiction to tobacco. Swiss company Cytos Biotechnology released the findings of the trial at the American Society of Clinical Oncology's annual meeting in Florida yesterday.
Prof Jacques Cornuz said the results were exciting. "The data clearly suggests that antibodies against nicotine are effective in helping people quit smoking," he said.

"I believe that the vaccine approach has the potential to dramatically alter the way we will treat smoking addiction in the future." Cytos plans more human trials in the US and Europe. Vaccine dosages and the number of injections will be increased to ensure nicotine does not enter the brain. If the vaccine is approved by health authorities worldwide, it could be on the market by 2010.
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